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About the GCRC
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About the GCRC
The GCRC is funded by the National Institutes of Health (NIH) to provide facilities and
resources for peer-reviewed clinical studies. Our goal is to play a major role in
facilitating scientific advances which will impact broadly across all human health. We are
here to serve our volunteer research subjects, investigators, and the public. The GCRC helps
investigators conduct research with human subjects under the highest standards of safety.
Multidisciplinary Research Facility
The GCRC is a multidisciplinary research facility, with specialized
cores to facilitate therapeutic product development and nutrition research. GCRC funding
includes hospitalization and outpatient clinic costs for human research subjects. The Center
provides a milieu for the study of a broad spectrum of human pathophysiology and disease (see
Major Areas of Investigation, below). Because its primary focus
is research, the GCRC enables the study of unusual diseases or commonly encountered clinical
disorders under conditions or supervision that could not readily be obtained in primary
clinical care facilities.
In addition to the primary clinic at the University of Washington Medical Center, the GCRC has
a pediatric satellite located at Children's Hospital and Regional Medical Center. While the
specialized cores are located at UWMC, services extend to investigators at both locations.
Find out about the GCRC's range of services or prepare an
application to use the GCRC for your research.
Training and Career Development
The GCRC is a resource for anyone interested in clinical research, especially
junior faculty who are just beginning a career in the field and
residents who are considering it. For investigators who are
seeking Clinical K awards that would use GCRC resources, we offer
mentoring throughout the grant process. We can also help young
investigators manage their clinical trials and develop optimal tools to help collect data.
For ongoing training, all investigators, research staff and students are welcome to take
advantage of the GCRC's free clinical research courses and seminars.
In addition to regularly scheduled events, GCRC core managers offer individualized training. For
more information about GCRC units, click here.
Adherence to Federal Guidelines
The GCRC and PCRC adhere to all applicable federal guidelines, including those assuring equal
representation of all ethnic and gender groups. Any investigator utilizing GCRC or PCRC
facilities is expected to follow the federal guidelines on protection of human subject's
rights.
Anesthesiology:
pain control in children, post-operative agitation in children.
Cardiology:
Atherosclerosis progression; nonintervention technology in assessment of cardiac function, role of exercise in modulating heart failure, regulating of blood clotting during heart transplant in children.
Endocrinology and Metabolism:
Pathophysiology of type I and type II diabetes; mechanism of insulin secretion and role of other gastrointestinal peptides; complications of diabetes; mechanism of body weight regulation; pathophysiology of genetic and acquired hyperlipidemias; infertility in males, etiology of childhood diabetes.
Gastroenterology:
Interventional therapy for chronic hepatitis, treatment for children infected with hepatitis.
Gene and Cell Therapy:
Adoptive immunotherapy for HIV and metastatic melanoma using genetically modified T-cells; T cell therapy for lymphoma, HSV-TK gene therapy for melanoma.
Hematology:
Effect of recombinant colony-stimulating factors in cyclic and chronic neutropenia and in normal neutrophil kinetics; progenitor cell mobilization in sickle cell anemia.
HIV:
Pain control and HIV, novel therapeutics for HIV, methods for monitoring HIV infection, HIV infection in pregnancy.
Immunology:
Acquired and genetic syndromes of diminished resistance to infection. Chronic neutropenia, study of immunity and cancer.
Infectious Diseases:
Multidrug therapy for HIV infection, multidrug and biological response modifier therapy for hepatitis B and C, kinetics of HSV infections, natural remedies for urinary tract infections, HSV infections post transplant.
Nephrology:
Kidney transplant rejection studies, glomerulosclerosis in children, kidney transplants in children.
Neurology:
New therapies for multiple sclerosis.
Obstetrics and Gynecology:
Role of central obesity in postmenopausal women and in placenta previa.
Oncology:
New transplant therapies for leukemia and lymphoma, vaccine therapy for breast and ovarian cancer, immunotherapy for cancer, novel strategies for treating brain tumors in children, T cell therapy and immune therapy for melanoma, antibody therapy for lymphoma, new treatment for sarcoma in adults and children.
Pharmacology:
Drug metabolism in pregnancy, pharmacology of anti-viral agents, drug levels in mothers milk.
Psychiatry:
Hormonal control of sleep in old age. hormonal control of brain function, childhood schizophrenia, adolescent patterns of self-harm, studies of family depression.
Pulmonary:
New therapies for cystic fibrosis (CF), quality of life studies in CF, genetic diagnosis of CF, chronic lung disease in infants, role of environmental exposures in lung injury, immune based therapies for sarcoidosis, childhood asthma.
Rehabilitation:
Hypnosis in disability related pain.
Rheumatology:
childhood arthritis treatments, cardiac disease in pediatric lupus.
AND MORE!
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