Here is a list of some of the articles that have been published or accepted for publication
based on assistance given and/or research performed at the University of Washington GCRC and
the Pediatric CRC at Children's Hospital and Regional Medical Center.
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| Aiello EJ;Yasui Y;Tworoger SS;Ulrich CM;Irwin ML;Bowen D;Schwartz RS;Kumai C;Potter JD;McTiernan A; |
Effect of a yearlong, moderate-intensity exercise intervention on the occurrence and severity of menopause symptoms in postmenopausal women |
Menopause11.4: 382-3882004 Jul |
| Albert TSE; Duchateau PN; Deeb SS; Pullinger CR; Cho MH; Deilbron DC; Malloy MJ; Kane JP; Brown BG |
Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL |
J Lipid Res2005 Mar |
| Amory JK;Bremner WJ; |
Oral Testosterone in Oil Plus Dutasteride in Men: A Pharmacokinetic Study |
J Clin Endocrinol Metab.2005 Feb 15 |
| Austin MA; Zhang C; Humphries SE; Chandler WL; Talmud PJ; Edwards KL; Leonetti DL; McNeely MJ; Fujimoto WY |
Heritability of C-reactive protein and association with apolipoprotein E genotypes in Japanese Americans. |
Ann Hum Genet2004 May |
| Austin MA;Edwards KL;McNeely MJ;Chandler WL;Leonetti DL;Talmud PJ;Humphries SE;Fujimoto WY; |
Heritability of multivariate factors of the metabolic syndrome in nondiabetic Japanese americans |
Diabetes53.4: 1166-11692004 Apr |
| Badzioch MD, Igo RP Jr, Gagnon F, Brunzell JD, Krauss RM, Motulsky AG, Wijsman EM, Jarvik GP. |
Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan. |
Arterioscler Thromb Vasc Biol2004 Oct |
| Bergt C; Pennathur S; Fu X; Byun J; O'Brien K; McDonald T; Singh P; Anantharamaiah GM; Chait A; Brunzell J; Geary RL; Oram JF; Heinecke JW |
The myeloperoxidase product hypocholorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport |
P Natl Acad Sci USA101.35: 13032-130372004 Aug |
| Boright AP; Paterson AD; Mirea L; Bull SB; Mowjoodi A; Scherer SW; Zinman B; DCCT/EDIC Research Group |
Genectic Variation at the ACE Gene IS Associated With Persistent Microalbuminuria and Severe Nephrophaty in Type 1 Diabetes: The DCCT/EDIC Genetics Study |
Diabetes54: 1238-12442004 Dec |
| Brooks-Worrell BM;Greenbaum CJ;Palmer JP;Pihoker C; |
Autoimmunity to islet proteins in children diagnosed with new-onset diabetes |
J Clin Endocrinol Metab89.5: 2222-22272004 May |
| Callahan HS; Cummings DE; Pepe MS; Breen PA; Matthys CC; Weigle DS |
Postprandial suppression of plasma ghrelin level is proportional to ingested caloric load but does not predict inter-meal interval in humans |
J Clin Endocrinol Metab89: 1319-13242004 |
| Carr DB, Utzschneider KM, Hull RL, Kodama K, Retzlaff BM, Brunzell JD, Shofer JB, Fish BE, Knopp RH, Kahn S . |
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome |
Diabetes2004 Aug |
| Carr DB;Utzschneider KM;Boyko EJ;Asberry PJ;Hull RL;Kodama K;Callahan HS;Matthys CC;Leonetti DL;Schwartz RS;Kahn SE;Fujimoto WY; |
A reduced-fat diet and aerobic exercise in Japanese Americans with impaired glucose tolerance decreases intra-abdominal fat and improves insulin sensitivity but not beta-cell function |
Diabetes54.2: 340-3472005 Feb |
| Carr MC;Brunzell JD; |
Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk |
J Clin Endocrinol Metab89.6: 2601-26072004 Jun |
| Chait A; Han CY; Oram JF; Heinecke JW |
Thematic review series: the Immunie System and Atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease? |
Journal of Lipid Research46: 389-4032005 Jan |
| Cherrier MM;Matsumoto AM;Amory JK;Ahmed S;Bremner W;Peskind ER;Raskind MA;Johnson M;Craft S; |
The role of aromatization in testosterone supplementation: effects on cognition in older men |
Neurology64.2: 290-2962005 Jan 25 |
| Chiou CF, Weaver MR, Bell MA, Lee TA, Krieger JW. |
Development of the multi-attribute Pediatric Asthma Health Outcome Measure (PAHOM). |
Int J Qual Health Care17.1: 23-302005 Feb |
| Chubak J;Tworoger SS;Yasui Y;Ulrich CM;Stanczyk FZ;McTiernan A; |
Associations between reproductive and menstrual factors and postmenopausal sex hormone concentrations |
Cancer Epidemiol Biomarkers Prev13.8: 1296-13012004 Aug |
| Coviello AD;Matsumoto AM;Bremner WJ;Herbst KL;Amory JK;Anawalt BD;Sutton PR;Wright WW;Brown TR;Yan X;Zirkin BR;Jarow JP; |
LOW DOSE HUMAN CHORIONIC GONADOTROPIN MAINTAINS INTRATESTICULAR TESTOSTERONE IN NORMAL MEN WITH TESTOSTERONE INDUCED GONADOTROPIN SUPPRESSION |
J Clin Endocrinol Metab.2005 Feb 15 |
| Cummings DE; Frayo RS; Marmonier C; Aubert R; Chapelot D |
Plasma ghrelin levels and hunger scores among humans initiating meals voluntarily in the absence of time- and food-related cues |
Am J Physiol Endocrinol Metab287: E297-3042004 |
| Dale O;Sheffels P;Kharasch ED; |
Bioavailabilities of rectal and oral methadone in healthy subjects |
Br J Clin Pharmacol58.2: 156-1622004 Aug |
| Danzi S, Klein I, Portman MA |
Effect of triiodothyronine on gene transcription during cardiopulmonary bypass in infants with ventricular septal defect. |
Am J Cardiol15.95: 787-7892005 Mar |
| DCCT/EDIC Research Group Box NDIC/DCCT; Klein RL; McHenry MB; Lok KH; Hunter SJ; Le NA; Jenkins AJ; Zheng D; Semler A; Page G; Brown WV; Lyons TJ; Garvey WT |
Apolipoprotein C-III protein concentrations and gene polymorphisms in Type 1 diabetes: Associations with microvascular disease complications in the DCCT/EDIC cohort |
Journal of Diabetes and its Complications19.1: 18-252005 Jan |
| Deterding R; Retsch-Bogart G; Milgram L; Gibson R; Daines C; Zeitlin PL; Milla C; Marshall B; LaVange L; Engels J; Mathews D; Gorden JoAnn; Schaberg A; Williams J; Ramsey B |
Safety and Tolerability of Denufosol Tetrasodium Inhalation Solution, a Novel P2Y2 Receptor Agonist: Results of a Phase 1/Phase 2 Multicenter Study in Mild to Moderate Cystic Fibrosis |
Pediatric Pulmonology39: 339-3482004 Nov |
| Disis ML;Goodell V;Schiffman K;Knutson KL; |
Humoral epitope-spreading following immunization with a HER-2/neu peptide based vaccine in cancer patients |
J Clin Immunol24.5: 571-5782004 Sep |
| Disis ML;Schiffman K;Guthrie K;Salazar LG;Knutson KL;Goodell V;dela Rosa C;Cheever MA; |
Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein--based vaccine |
J Clin Oncol22.10: 1916-19252004 May 15 |
| For the PCTG1-22 Study Team. Hitti J; Frenkel LM; Stek AM; Nachman SA; Baker D; Gonzalez-Gercia A; Provisor Arthur; Thorpe EM; Paul ME; Foca M; Gandia J; Huang S; Wei LJ; Stevens LM; Watts DH; McNamara J |
Maternal Toxicity with Continuous Nevirapine in Pregnancy: Results from PACTG 1022 |
JAIDS36.3: 772-7762004 Jul |
| Foster-Schubert KE;McTiernan A;Frayo RS;Schwartz RS;Rajan KB;Yasui Y;Tworoger SS;Cummings DE; |
Human plasma ghrelin levels increase during a one-year exercise program |
J Clin Endocrinol Metab90.2: 820-8252005 Feb |
| Frank LL;Sorensen BE;Yasui Y;Tworoger SS;Schwartz RS;Ulrich CM;Irwin ML;Rudolph RE;Rajan KB;Stanczyk F;Bowen D;Weigle DS;Potter JD;McTiernan A; |
Effects of exercise on metabolic risk variables in overweight postmenopausal women: a randomized clinical trial |
Obes Res13.3: 615-6252005 Mar |
| Greenbaum C;Seidel K;Pihoker C; |
The case for intravenous arginine stimulation in lieu of mixed-meal tolerance tests as outcome measure for intervention studies in recent-onset type 1 diabetes |
Diabetes Care27.5: 1202-12042004 May |
| Groh V; Li YQ; Cioca D; Hunder NN; Wang W; Riddell SR; Yee Cassian; Spies T |
Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells |
P Natl Acad Sci USA102.18: 6461-64662005 Apr |
| Gunther DF;Eugster E;Zagar AJ;Bryant CG;Davenport ML;Quigley CA; |
Ascertainment bias in Turner syndrome: new insights from girls who were diagnosed incidentally in prenatal life |
Pediatrics114.3: 640-6442004 Sep |
| Hayashi T; Boyko EJ; Leonetti DL; McNeely MH; Newell-Morris L; Kahn SE; Fujimoto WY |
Visceral adiposity is an independent predictor of incident hypertension in Japanese Americans |
Ann Intern Med2004 Jun |
| Hebert MF; Carr DB; Anderson GD; Blough D; Green GE; Brateng DA; Kantor E; Benedetti TJ; Easterling TR |
Pharmacokinetics and Pharmacodynamics of Atenolol During Pregnancy and Postpartum |
J Clin Pharmacol2005 Jan |
| Herbst KL;Coviello AD;Page S;Amory JK;Anawalt BD;Bremner WJ; |
A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men |
J Clin Endocrinol Metab89.12: 5959-59652004 Dec |
| Irwin ML;McTiernan A;Baumgartner RN;Baumgartner KB;Bernstein L;Gilliland FD;Ballard-Barbash R; |
Changes in body fat and weight after a breast cancer diagnosis: influence of demographic, prognostic, and lifestyle factors |
J Clin Oncol23.4: 774-7822005 Feb 1 |
| Irwin ML;McTiernan A;Bernstein L;Gilliland FD;Baumgartner R;Baumgartner K;Ballard-Barbash R; |
Physical activity levels among breast cancer survivors |
Med Sci Sports Exerc36.9: 1484-14912004 Sep |
| Irwin ML;Tworoger SS;Yasui Y;Rajan B;McVarish L;LaCroix K;Ulrich CM;Bowen D;Schwartz RS;Potter JD;McTiernan A; |
Influence of demographic, physiologic, and psychosocial variables on adherence to a yearlong moderate-intensity exercise trial in postmenopausal women |
Prev Med39.6: 1080-10862004 Dec |
| Jin Y; Mazza C; Christie JR; Giliani S; Fiorini M; Mella P; Gandellini F; Stewart DM; Zhu Q; Nelson DL; Notarangelo LD; Ochs HD |
Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation |
Blood104.13: 4010-40192004 Jul |
| Johns DO; Kills RL; Morgan MS |
Evaluation of dynamic headspace with gas chromatography/mass spectrometry for the determination of 1, 1, 1 -trichloroethan, trichloroethanol, and trichloroacetic acid in biological samples |
Journal of Chromatography B817: 255-2612004 Dec |
| Kashuba AD;Tierney C;Downey GF;Acosta EP;Vergis EN;Klingman K;Mellors JW;Eshleman SH;Scott TR;Collier AC; |
Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results |
AIDS19.2: 145-1522005 Jan 28 |
| Kharasch ED;Hoffer C;Whittington D; |
Influence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate |
Anesthesiology101.3: 738-7432004 Sep |
| Kharasch ED;Hoffer C;Whittington D; |
The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone |
Br J Clin Pharmacol57.5: 600-6102004 May |
| Kharasch ED;Hoffer C;Whittington D;Sheffels P; |
Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone |
Clin Pharmacol Ther76.3: 250-2692004 Sep |
| Kharasch ED;Walker A;Hoffer C;Sheffels P; |
Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination |
J Clin Pharmacol45.1: 79-882005 Jan |
| Kharasch ED;Walker A;Hoffer C;Sheffels P; |
Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis |
Clin Pharmacol Ther76.5: 452-4662004 Nov |
| Kharasch ED;Whittington D;Hoffer C; |
Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate |
Anesthesiology101.3: 729-7372004 Sep |
| Krieger JW, Song L, Takaro T |
The Seattle-King County Healthy Homes Project: A Randomized, Controlled Trial of a Community Health Worker Intervention to Decrease Exposure to Indoor Asthma Triggers among Low-income Children. |
Am J Public Health95: 652-6592005 |
| Levy RL; Whitehead WE; Walker L; Feld AD; VonKorff M; Christie D; Garner MD; White CR |
Impact of learned illness behavior on health costs |
Gastroenterology126: A-2472004 |
| Levy RL; Whitehead WE; Walker LS; Von Korff M; Feld AD; Garner M; Christie D |
Increased somatic complaints and health-care utilization in children: effects of parent IBS status and parent response to gastrointestinal symptoms |
Am J Gastroenterol99.12: 2442-24512004 Dec |
| Lewis KE; Kirk EA; McDonald TO; Wang S; Wight TN; O'Brien KD; Chait A |
Increase in Serum Amyloid A Evoked by Dietary Cholesterol Is Associated With Increased Atherosclerosis in Mice |
Circulation110: 540-5452004 Apr |
| Liles WC;Rodger E;Broxmeyer HE;Dehner C;Badel K;Calandra G;Christensen J;Wood B;Price TH;Dale DC; |
Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist |
Transfusion45.3: 295-3002005 Mar |
| Luo D;Gilliam LK;Greenbaum C;Bekris L;Hampe CS;Daniels T;Richter W;Marcovina SM;Rolandsson O;Landin-Olsson M;Kockum I;Lernmark A; |
Conformation-dependent GAD65 autoantibodies in diabetes |
Diabetologia47.9: 1581-15912004 Sep |
| Masedo AI;Hanley M;Jensen MP;Ehde D;Cardenas DD; |
Reliability and validity of a self-report FIM (FIM-SR) in persons with amputation or spinal cord injury and chronic pain |
Am J Phys Med Rehabil84.3: 167-1762005 Mar |
| McLaughlin T; Abbasi F; Lamendola C; Frayo RS; Cummings DE |
Plasma Ghrelin Concentration Are Decreased in Insulin-Resistant Obese Adults Relative to Equially Obese Insulin-Sensitive Controls |
J Clin Endocrinol Metab89.4: 1630-16352004 Apr |
| McTiernan A;Tworoger SS;Rajan KB;Yasui Y;Sorenson B;Ulrich CM;Chubak J;Stanczyk FZ;Bowen D;Irwin ML;Rudolph RE;Potter JD;Schwartz RS; |
Effect of exercise on serum androgens in postmenopausal women: a 12-month randomized clinical trial |
Cancer Epidemiol Biomarkers Prev13.7: 1099-11052004 Jul |
| McTiernan A;Tworoger SS;Ulrich CM;Yasui Y;Irwin ML;Rajan KB;Sorensen B;Rudolph RE;Bowen D;Stanczyk FZ;Potter JD;Schwartz RS; |
Effect of exercise on serum estrogens in postmenopausal women: a 12-month randomized clinical trial |
Cancer Res64.8: 2923-29282004 Apr 15 |
| Moe KE; |
Hot flashes and sleep in women |
Sleep Med Rev8.6: 487-4972004 Dec |
| Montgomery RB;Makary E;Schiffman K;Goodell V;Disis ML; |
Endogenous anti-HER2 antibodies block HER2 phosphorylation and signaling through extracellular signal-regulated kinase |
Cancer Res65.2: 650-6562005 Jan 15 |
| Moss RB;Mayer-Hamblett N;Wagener J;Daines C;Hale K;Ahrens R;Gibson RL;Anderson P;Retsch-Bogart G;Nasr SZ;Noth I;Waltz D;Zeitlin P;Ramsey B;Starko K; |
Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease |
Pediatr Pulmonol39.3: 209-2182005 Mar |
| Mozaffarian D;Rimm EB;King IB;Lawler RL;McDonald GB;Levy WC; |
trans fatty acids and systemic inflammation in heart failure |
Am J Clin Nutr80.6: 1521-15252004 Dec |
| O'Brien KD; Lewis K; Fishcher JQ; Johnson P; Hwang JY; Knopp EA; Kinsella MG; Barret PHR; Chait A; Wight TN |
Smooth muscle cell biglycan overexpression results in incresed lipoprotein retention on extracellular matrix: implications for the retention of lipoproteins in atherosclerosis |
Atherosclerosis177.1: 29-352004 Jul |
| O'Brien KD;Zhao XQ;Shavelle DM;Caulfield MT;Letterer RA;Kapadia SR;Probstfield JL;Otto CM; |
Hemodynamic effects of the angiotensin-converting enzyme inhibitor, ramipril, in patients with mild to moderate aortic stenosis and preserved left ventricular function |
J Investig Med52.3: 185-1912004 Apr |
| Ochs HD, Notarangelo LD |
X-linked immunodeficiencies |
Curr Allergy Asthma Rep - no impact4.5: 339-3482004 Sep |
| Ochs HD; Pinciaro PJ; The Octagam Study Group |
Octagam 5% an Intravenous IgG Product, is Efficacious and Well Tolerated in Subjects with Primary Immunodeficiency Diseases |
Journal of Clinical Immunology24.3: 309-3142004 May |
| Page ST;Herbst KL;Amory JK;Coviello AD;Anawalt BD;Matsumoto AM;Bremner WJ; |
Testosterone administration suppresses adiponectin levels in men |
J Androl26.1: 85-922005 Jan |
| Pennathur S; Bergt C; Shao B; Byun J; Kassim SY; Green PS; McDonald TO;Brunzell J; Chait A; Oram JF; O'Brien K; Geary RL; Heinecke JW |
Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain Hight Density Lipoprotein Damaged by Reactive Nitrogen Species |
J Biol Chem279.41: 42977-429832004 Jul |
| Pierce D; Chen Y; Hurtle W; Morgan M |
Exponential modeling, washout curve reconstruction, and estimation of half-life of toluene and its metabolites |
J Toxicol Environ Health A67.14: 1131-11582004 Jul |
| Portman MA;Fearneyhough C;Karl TR;Tong E;Seidel K;Mott A;Cohen G;Tacy T;Lewin M;Permut L;Schlater M;Azakie A; |
The Triiodothyronine for Infants and Children Undergoing Cardiopulmonary Bypass (TRICC) study: design and rationale |
Am Heart J148.3: 393-3982004 Sep |
| Quigley J, Yang Z, Worthington M, Phillips J, Sabo K, Sabath D, Berg C, Sassa S, Wood B, Abkowitz J |
Identification of a Human Heme Exporter that Is Essential for Erythropoiesis |
Cell118.6: 757-7662004 Jul |
| Robertson PR |
AIRarg and AIRgluc as Predictors of Insulin Secretory Reserve |
Transplant P2004 May |
| Roder ME;Kahn SE; |
Suppression of Beta-cell secretion by somatostatin does not fully reverse the disproportionate proinsulinemia of type 2 diabetes |
Diabetes53 Suppl 3: S22-S252004 Dec |
| SEARCH for Diabetes in Youth Study Group (Pihoker, C) |
SEARCH for Diabetes in Youth: a Multi-Center Study of the Prevalence, Incidence and Classification of Diabetes Mellitus in Youth |
Control Clin Trials25: 458-4712004 Oct |
| Takaro TK, Krieger JW and Song L. |
Effect of environmental interventions to reduce exposure to asthma triggers in homes of low-income children in Seattle |
Exp. Anal. Env. Epid. 14Suppl 1: S133-S1432004 |
| Tsai EC; Brown JA; Veldee MY; Anderson GJ; Chait A; Brunzell JD |
Potential of essential fatty acid deficiency with extremely low fat diet in lipoprotein lipase deficiency during pregnancy: A case report |
BMC Pregnancy and Childbirth2004 Dec |
| Tworoger SS;Chubak J;Aiello EJ;Yasui Y;Ulrich CM;Farin FM;Stapleton PL;Irwin ML;Potter JD;Schwartz RS;McTiernan A; |
The effect of CYP19 and COMT polymorphisms on exercise-induced fat loss in postmenopausal women |
Obes Res12.6: 972-9812004 Jun |
| Utzschneider KM; Carr DB; Hull RL; Kodama K; Shofer JB; Retzlaff BM; Knopp RH; Kahn SE |
Impact of intra-abdominal fat and age on insulin sensitivity and beta-cell function |
Diabetes2004 Nov |
| Vitiello MV;Larsen LH;Moe KE; |
Age-related sleep change: Gender and estrogen effects on the subjective-objective sleep quality relationships of healthy, noncomplaining older men and women |
J Psychosom Res56.5: 503-5102004 May |
| Wade NA; Unadkat JD; Huang S; Shapiro DE; Mathias A; Yasin S; Ciupak G; Watts DH; Delke I; Rathore M; Hitti J; Frenkel L; Samelson R; Smith ME; Mofenson L; Burchett SK |
Pharmacokinetics and Sfety of Stavudine in HIV-Infected Pregnant Women and Their Infants: Pediatric AIDS Clinical Trials Group Protocol 332 |
J Infectious Diseases190: 2167-21742004 Jun |
| Wang J;Press OW;Lindgren CG;Greenberg P;Riddell S;Qian X;Laugen C;Raubitschek A;Forman SJ;Jensen MC; |
Cellular immunotherapy for follicular lymphoma using genetically modified CD20-specific CD8+ cytotoxic T lymphocytes |
Mol Ther9.4: 577-5862004 Apr |
| Winter HR;Trapnell CB;Slattery JT;Jacobson M;Greenspan DL;Hooton TM;Unadkat JD; |
The effect of clarithromycin, fluconazole, and rifabutin on dapsone hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283) |
Clin Pharmacol Ther76.6: 579-5872004 Dec |
| Winter HR;Trapnell CB;Slattery JT;Jacobson M;Greenspan DL;Hooton TM;Unadkat JD; |
The effect of clarithromycin, fluconazole, and rifabutin on sulfamethoxazole hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283) |
Clin Pharmacol Ther76.4: 313--3222004 Oct |